Genetics

Medical Mysteries

2-year-old S’pore boy is one of estimated 400 in world with disease caused by single altered gene

Teyden Hamilton Ho, who has Zhu-Tokita-Takenouchi-Kim syndrome, with his father, Ho Jun Han, and mother, Tizane Woo.

Medical Mysteries

Rare disorder leaves toddler struggling to produce cell energy

Little Oliver Soh began having seizures and showed signs of developmental delay within months of his birth. The toddler, seen here with his father, Keltonn Soh, and mother, Leow Kai Wen, has primary coenzyme Q10 deficiency.

Medical Mysteries

Work stress led woman to discover genetic condition that looks like heart attack

Cardiologist Tang Hak Chiaw and his patient Christina Chua, who has the genetic heart condition hypertrophic cardiomyopathy.

Medical Mysteries

Girl born with skin missing from her scalp, body, arms and legs, treated with her own lab-grown skin

Siti Abdullah (right) with her husband Abdul Rahman and their daughter Sumayyah, who was born without skin on nearly 40 per cent of her body.

Public consultation on proposed laws to better protect genetic information in Singapore

To allow more people here to benefit from genetic testing, which examines a person’s DNA, RNA, chromosomes, or genes – national programmes are being introduced to improve access to specific tests.

Child died in Chinese biotech firm’s gene-editing trial

Shanghai-based HuidaGene Therapeutics attributed the child’s death to acute respiratory distress syndrome as part of a severe immune reaction to the gene-editing therapy.

Medical Mysteries

Dad overhauls his lifestyle to become a living liver donor for his toddler with rare condition

Service staff Noel Joshua Selvanathan with his son Isaiah Luiz Noel, who was diagnosed with a rare genetic disorder called Alagille Syndrome.

Death of girl in Chinese gene-editing trial kept secret: Report

Mei’s parents paid more than US$800,000 (S$1 million) to fund the experimental genetic therapy, but were not adequately informed about the risks, the Science and Retraction Watch report said.

Medical Mysteries

When back pain turns out to be cancer – and something more

Cancer survivor Ranald Lai, who has also Li-Fraumeni syndrome - a rare genetic disorder that increases a person’s cancer risks - with his doctor, senior medical oncologist Valerie Yang.

Medical Mysteries

Toddler’s rare diagnosis gives family answers to her developmental delays

Three-year-old Tabitha Lowe is diagnosed with Okur-Chung Neurodevelopmental Syndrome (OCNDS), a rare condition first identified in 2016. She is blowing bubbles with her father Joshua Lowe, 35, mother Tiffany Tan, 34, and younger brother Judah, one.

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MDDI (P) 046/10/2025. Published by SPH Media Limited, Co. Regn. No.202120748H. Copyright © 2026 SPH Media Limited. All rights reserved.