Wuhan markets sold mink, civets long before Covid-19 emerged, says study

A security guard stands outside the Huanan Seafood Wholesale Market in Wuhan, on Jan 24, 2020. PHOTO: AFP

WASHINGTON (BLOOMBERG, REUTERS) - Chinese markets linked to some of the earliest Covid-19 cases were illegally selling a range of wildlife from which the coronavirus may have spread, according to a study published less than two weeks after US President Joe Biden ordered a deeper probe into the pandemic's genesis.

Mink, masked palm civets, raccoon dogs, Siberian weasels, hog badgers and Chinese bamboo rats were among 38 animal species sold live at markets in Wuhan from May 2017 to November 2019, researchers said on Monday (June 7) in a paper in the journal Scientific Reports originally submitted last October.

The hunt for Covid-19's origins has become increasingly political amid criticism that the Chinese government has not been open and transparent with key information, including activities in a Wuhan lab studying coronaviruses.

The new findings support the conclusions of a World Health Organisation-led research mission in early 2021 that concluded that Sars-CoV-2 most likely spilled over to humans from animals - either directly from a bat or via another mammal, possibly one sold at the Huanan seafood and fresh produce market in central Wuhan.

"This report clearly places Sars-CoV-2 susceptible animals smack in the middle of Wuhan," said microbiology and immunology expert Robert Garry from Tulane University in New Orleans, who was not involved in the research. It is a major revelation, he said in an e-mail.

Access to the detailed data in the study was serendipitous, the researchers said.

The findings were based on routine monthly surveys of shops selling live wild animals as pets or for food across Wuhan in the years before Covid-19 emerged at the end of 2019, the authors said. That unrelated study was intended to identify the source of a tick-borne disease.

"While we caution against the mis-attribution of Covid-19's origins, the wild animals on sale in Wuhan suffered poor welfare and hygiene conditions and we detail a range of other zoonotic infections they can potentially vector," lead author Xiao Xiao, from the Lab Animal Research Centre at Hubei University of Chinese Medicine in Wuhan, and colleagues wrote.

Both wild-caught and farmed non-domesticated species were sold - alive, caged, stacked and in poor condition - by 17 vendors, the researchers said. None posted an origin certificate or quarantine certificate, "so all wildlife trade was fundamentally illegal", they said.

The WHO-led research team reported that market authorities claimed all live and frozen animals sold in the Huanan market were acquired from farms officially licensed for breeding, and it found no verified reports of live mammals being sold around 2019. The market was shut down at 1am on Jan 1, 2020.

"This paper is affirmative evidence that there was obfuscation regarding which animals were being sold at the wet markets in Wuhan," Professor Garry said.

China temporarily banned all wildlife trade on Jan 26, 2020, and permanently banned eating and trading terrestrial wild animals for food a month later.

Before the ban, most stores offered butchering services, done on site, with considerable implications for food hygiene and animal welfare. Marmots - large ground squirrels - selling for more than US$25 (S$33) a kilogram, were the most expensive, while raccoon dogs and badgers were priced at about US$15-US$20 a kg, the researchers said.

"This group was able to learn a huge amount from vendors in these stalls, who were even willing to discuss openly that they were selling illegal wildlife," said Dr Michael Worobey, head of ecology and evolutionary biology at the University of Arizona in Tucson, who was not involved in the study.

"It is hard to imagine them being so transparent with government authorities or even the WHO. This serves as a reminder that less 'official' investigations can play a huge role," he said.

While the prevailing theory among virologists is that Covid-19 originated in bats and made its way into humans via an intermediary animal, efforts to pin down the details or identify any infected animals have been unsuccessful for the past year and a half. In part because of that futile attempt, combined with restrictions from China in the effort to gather information, some scientists have started calling for a more detailed investigation into the lab-leak theory.

President Biden directed his intelligence agencies to delve deeper into the issue last month, after he received a report on the origins earlier in May that detailed the scientific divide over whether Sars-CoV-2 arose naturally in animals or if it was leaked from the Wuhan Institute of Virology, one of the world's foremost laboratories working on coronaviruses.

Mr Biden asked for another update in 90 days.

Any finding of a coronavirus closely related to Sars-CoV-2 circulating in wild animals would likely quell suspicions that the pandemic virus was created in a lab, said Associate Professor Joel Wertheim from the University of California, San Diego, who studies viral molecular epidemiology. Still, there is no guarantee that such a virus will ever be found.

"We don't even know, if there's an intermediate species, which one we're looking for," he said over Zoom. "And also, if it was in a market beforehand, it's not any more."

The Wuhan Institute of Virology. A report on the origins of Covid-19 by a US government national laboratory concluded that the hypothesis of a virus leak from a Chinese lab in Wuhan is plausible and deserves further investigation, the Wall Street Journal said. PHOTO: AFP

Meanwhile, a report on the origins of Covid-19 by a US government national laboratory concluded that the hypothesis of a virus leak from a Chinese lab in Wuhan is plausible and deserves further investigation, the Wall Street Journal (WSJ) said on Monday (June 7), citing people familiar with the classified document.

The study was prepared in May 2020 by the Lawrence Livermore National Laboratory in California and was referred to by the US State Department when it conducted an inquiry into the pandemic's origins during the final months of the Trump administration, the WSJ report said.

Lawrence Livermore's assessment drew on a genomic analysis of the Covid-19 virus, the Journal said. Lawrence Livermore declined to comment on the Wall Street Journal report.

Mr Biden said last month he had ordered aides to find answers to the origin of the virus.

US intelligence agencies are considering two likely scenarios - that the virus resulted from a laboratory accident or that it emerged from human contact with an infected animal - but they have not come to a conclusion, Mr Biden said.

A still-classified US intelligence report circulated during former president Donald Trump's administration alleged that three researchers at China's Wuhan Institute of Virology became so ill in November 2019 that they sought hospital care, US government sources have said.

US officials have accused China of not being transparent about the virus' origins, a charge Beijing has denied.

Separately, Dr Mike Ryan, a top World Health Organisation official said on Monday the WHO cannot compel China to divulge more data on Covid-19's origins, while adding that it will propose studies needed to take understanding of where the virus emerged to the next level.

Earlier this month, US infectious disease expert Anthony Fauci called on China to release the medical records of nine people whose ailments might provide vital clues into whether Covid-19 first emerged as the result of a lab leak.

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