Will AI one day win a Nobel Prize?

STOCKHOLM - Artificial intelligence (AI) is already disrupting industries from banking and finance to film and journalism, and scientists are investigating how it might revolutionise their field – or even win a Nobel Prize.

In 2021, Japanese scientist Hiroaki Kitano proposed what he dubbed the “Nobel Turing Challenge”, inviting researchers to create an “AI scientist” capable of autonomously carrying out research worthy of a Nobel Prize by 2050.

Some scientists are already hard at work seeking to create an AI colleague worthy of a Nobel, with the 2024 laureates to be announced between Oct 7 and 14.

And in fact, there are around 100 “robot scientists” already, according to Professor Ross King of machine intelligence at Chalmers University in Sweden.

In 2009, Prof King published a paper in which he and a group of colleagues presented “Robot Scientist Adam” – the first machine to make scientific discoveries independently.

“We built a robot which discovered new science on its own, generated novel scientific ideas and tested them and confirmed that they were correct,” Prof King told AFP.

The robot was set up to form hypotheses autonomously, and then design experiments to test these out.

It would even programme laboratory robots to carry out those experiments, before learning from the process and repeating.

The robot – named Adam – was tasked with exploring the inner workings of yeast and discovered “functions of genes” that were previously unknown in the organism.

In the paper, the robot scientist’s creators noted that while the discoveries were “modest”, they were “not trivial” either.

Later, a second robot scientist – named Eve – was set up to study drug candidates for malaria and other tropical diseases.

According to Prof King, robot scientists already have several advantages over an average human scientist.

“It costs less money to do the science, they work 24/7,” he explained, adding that they are also more diligent at recording every detail of the process.

At the same time, Prof King conceded that AI is far from being anywhere close to a Nobel-worthy scientist.

For that, they would need to be “much more intelligent” and able to “understand the bigger picture”.

Associate Professor Inga Strumke from the Norwegian University of Science and Technology said that for the time being, the scientific profession is safe.

“The scientific tradition is nowhere near being taken over by machines any time soon,” she told AFP.

However, Prof Strumke added that “doesn’t mean that it’s impossible”, adding that it is “definitely” clear that AI is having and will have an impact on how science is conducted.

One example of how it is already in use is AlphaFold – an AI model developed by Google DeepMind – which is used to predict the 3D structure of proteins based on their amino acid.

“We knew that there was some relation between the amino acids and the final three-dimensional shape of the proteins... and then we could use machine learning to find it,” Prof Strumke said.

She explained that the complexity of such calculations was too daunting for humans.

“We kind of have a machine that did something that no humans could do,” she said.

At the same time, for Prof Strumke, the case of AlphaFold also demonstrates one of the weaknesses of current AI models such as so-called neural networks.

They are very adept at crunching massive amounts of information and coming up with an answer, but not very good at explaining why that answer is correct.

So while the more than 200 million protein structures predicted by AlphaFold are “extremely useful”, they “don’t teach us anything about microbiology”, Prof Strumke said.

For her, science seeks to understand the universe and is not merely about “making the correct guess”.

Still, the ground-breaking work done by AlphaFold has led to pundits putting the minds behind it as front-runners for a Nobel Prize.

Google DeepMind’s director John Jumper and chief executive and co-founder Demis Hassabis were already honoured with the prestigious Lasker Award in 2023.

Analytics group Clarivate, which keeps an eye on potential Nobel science laureates, places the pair among the top picks for the 2024 candidates for the Prize in Chemistry, which will be announced on Oct 9.

Clarivate head David Pendlebury admits that while a 2021 paper by Dr Jumper and Dr Hassabis has been cited thousands of times, it would be out of character for the Nobel jury to award work so quickly after publication – as most discoveries that are honoured date back decades.

At the same time, he feels confident that it will not be too long before research aided by AI will win the most coveted of science prizes.

“I’m sure that within the next decade there will be Nobel Prizes that are somehow assisted by computation and computation these days is more and more AI,” he told AFP. AFP