Ketamine used to treat major depression in authorised settings

It is for patients who do not respond well to other forms of treatment; experts urge caution

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Ketamine, a controlled substance referred to as a party drug by those who abuse it, is now being used in authorised clinical settings in Singapore to treat patients with major depressive disorder (MDD) who are not responding well to other forms of treatment.

Esketamine has been approved by the authorities and used to treat two patients in Singapore. The modified version of ketamine is being administered via a nasal spray.

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A version of this article appeared in the print edition of The Straits Times on May 10, 2021, with the headline Ketamine used to treat major depression in authorised settings. Subscribe