A bus mounted a kerb and drove into pedestrians in Hong Kong's Sham Shui Po district on Friday (Sept 22) evening, Hong Kong media reported.
At least three people have died in the accident, which occurred at the junction of Yen Chow Street and Cheung Sha Wan Road around 6.40pm, the South China Morning Post reported.
A woman was pronounced dead on the scene, while two men aged 48 and 60 died in hospital.
More than 20 people were injured in the accident, Hong Kong's Apple Daily reported. Two are said to be in a critical condition.
The 44-year-old driver, who escaped unhurt, was taken away by police for questioning and was later arrested on suspicion of dangerous driving causing death.
Photos of the accident show rescuers trying to extract people from under the bus operated by Citybus, while paramedics tend to the injured at the busy intersection.
An eyewitness who gave his name only as Mr Chen told Apple Daily that he was passing by when the accident occurred.
He said several pedestrians were knocked over and at least two were trapped under the bus.
Some passengers on the bus also appeared to be injured.
The traffic accident is "one of the worst in recent years", SCMP reported.
It cited another accident in January where a bus run by Citybus crashed into road barriers, killing one person and injuring 17 others.