SilkAir will fly to Hangzhou in eastern China from June 27.
It will operate services four times a week using its A-319 and A-320 Airbus aircraft which features both business and economy class cabins, said SilkAir, the regional wing of Singapore Airlines, in a press release on Wednesday.
Hangzhou, the capital of the Zhejiang province, is known for its scenery and cultural sites. The city is centred largely around the West Lake and is famous for its Longjing or Dragon Well Green tea.
It is SilkAir's eighth destination in China, after Changsha, Chengdu, Chongqing, Kunming, Shenzhen, Wuhan and Xiamen. The airline first began operations to China in 1993.