President Halimah Yacob said yesterday that the shooting in Las Vegas was a horrific act of violence and should be strongly condemned.
"Deeply saddened by the shooting incident in Las Vegas which resulted in more than 50 dead and hundreds injured," she wrote on her Facebook page.
"It was a horrific act of violence against innocent people and should be strongly condemned.
"On behalf of the people of Singapore, I convey our deepest condolences to the United States. Our thoughts are with them and the families of those affected during this difficult time,'' she wrote.
Las Vegas police said 64-year-old retiree Stephen Paddock, armed with multiple assault rifles, opened fire at an outdoor country music festival from his 32nd-floor room in the Mandalay Bay Resort and Casino, killing at least 59 people and injuring more than 500 others, before killing himself.
It was the deadliest mass shooting in modern US history.
A barrage of gunfire was heard as terrified music fans desperately cowered on the open ground, hemmed in by fellow concertgoers, while others at the edge tried to flee.