SAN DIEGO, USA (REUTERS) - Marvel Studios' blockbuster movie Avengers: Endgame on Sunday (July 21) is poised to become the top-grossing film of all time, surpassing the record for global tickets sales set by the 2009 film Avatar, which pulled in nearly US$2.8 billion (S$3.81 billion) worldwide.

That's according Marvel studio head Kevin Feige, who at Comic-Con over the weekend unveiled a star-packed slate of new Marvel films in production, including The Eternals, with this cast member arguably getting the biggest cheers:

"Let me introduce Angelina Jolie!" said Marvel studio CEO Feige.

Jolie - who off-camera is often trying to save the world through her humanitarian efforts - will step into the role of Thena, one of the superhuman Eternals fighting to save the earth from evil forces.

Also on tap, a fourth Thor movie - but this time it's a woman who will take up the hammer.

"For us, there's only one person who could play that role," said Thor: Love and Thunder director, Taika Waikiki. "Please welcome to the stage, Natalie Portman!"

Portman's take on Thor is expected in the fall of 2021.

Rounding out a trifecta of powerful women, Scarlett Johansson was on-hand at Comic-Con's Hall H - where the convention's biggest panels are held - to unveil a trailer for Black Widow.

Johansson is returning to the role she made famous in the Avenger films, but this time in a standalone film without her superhero costars.

"If you had told me 10 years ago that I would be presenting footage in Hall H of the Black Widow standalone, it would have been incomprehensible," said Johansson. "It's kind of mind-blowing."

Marvel Studios, which is owned by Disney, also said the new slate of films will include a diverse cast of characters, including the first openly LGBTQ superhero.