The University of Chicago Booth School of Business will relocate its Asia Executive MBA programme from Singapore to Hong Kong in 2014.
The programme has run for 13 years in the Republic.
"We aspire to have a robust, ongoing presence in Singapore, and we are looking at options for continued and new programming in the region," said Mr Sunil Kumar, Chicago Booth dean and George Pratt Shultz Professor of Operations Management.
Chicago Booth is exploring space options for holding classes and other activities in Singapore after the Asia Executive MBA Program relocates.
Potential activities in Singapore include custom executive education, remote teaching, seminars, and alumni and community events.
Since the Singapore campus opened in 2000, more than 1,000 students have received their MBAs from the Asia Executive MBA program, and nearly 2,000 students from Booth's London and Chicago campuses have spent time on the Singapore campus.