Eyes a key route of infection by coronavirus, says Hong Kong study

It was assumed in the early stages of the coronavirus crisis that medical personnel would be sufficiently protected by wearing N95 face masks and protective clothing, and did not need specialist glasses. The latest findings from a Hong Kong universit
It was assumed in the early stages of the coronavirus crisis that medical personnel would be sufficiently protected by wearing N95 face masks and protective clothing, and did not need specialist glasses. The latest findings from a Hong Kong university report challenge that assumption. PHOTO: EPA-EFE

HONG KONG • The eyes are a key route by which the coronavirus infects humans, a study by the University of Hong Kong has found, in addition to the upper respiratory tract, which includes the nose, mouth and throat.

The study made public yesterday also found that Sars-Cov-2 - the strain of coronavirus that causes the Covid-19 disease - was up to 100 times more infectious than the severe acute respiratory syndrome (Sars) virus, or Sars-Cov, and bird flu viruses such as H5N1, reported newswire agency Xinhua.

The research team led by Dr Michael Chan Chi-wai, associate professor at the university's School of Public Health, found that the coronavirus is much more efficient in infecting the human conjunctiva - the tissue lining the surface of the eye - and the upper respiratory airways, and its level of infection is comparable to that observed for H1N1, the swine flu virus that caused a pandemic in 2009.

"This explains the higher transmissibility of Covid-19 than that of Sars. This study also highlights the fact that eyes may be an important route of Sars-Cov-2 human infection," Dr Chan said, according to the South China Morning Post (SCMP) in Hong Kong.

The research team had previously discovered that the coronavirus remains alive for up to seven days on smooth surfaces such as stainless steel, glass and plastic. It is therefore possible for people to get infected when they touch these surfaces with their hands and then touch their face.

This latest finding affirms advice from public health experts that people can lower their risk of infection by washing their hands regularly and not touching their faces, to avoid accidental transfer of the virus through their facial orifices.

The study, which was published in the latest issue of The Lancet Respiratory Medicine, comes as the number of Covid-19 cases reaches nearly four million worldwide, with more than 271,000 fatalities as of yesterday.

The Sars outbreak over 2002 and 2003 infected nearly 8,100 people worldwide and claimed 774 lives.

Dr Chan said: "Although there are signs that the Covid-19 epidemic is getting more stable in Hong Kong, the situation elsewhere in the world is still serious.

"There are still many new cases reported every day in, say, Russia and Europe. We should not let our guard down."

According to the SCMP report, it was assumed in the early stages of the coronavirus crisis that medical personnel would be sufficiently protected by wearing N95 face masks and protective clothing, and did not need specialist glasses. These latest findings by Dr Chan's team, it says, challenge that assumption.

The Covid-19 outbreak first came to light in late December, after cases were detected in the Chinese city of Wuhan.

Scientists who have studied the virus' source say it originated in an animal, and probably entered the human population in November.

SCMP also reported that a well-known respiratory specialist at Peking University, Dr Wang Guangfa, was suspected to have been infected by the coronavirus through his eyes.

The newspaper said that in late January, Dr Wang displayed symptoms of fever and catarrh, about three hours after his eye developed conjunctivitis on his return from Wuhan. He was later confirmed to have Covid-19.

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A version of this article appeared in the print edition of The Straits Times on May 09, 2020, with the headline Eyes a key route of infection by coronavirus, says Hong Kong study. Subscribe