GENEVA (AFP) - The UN rights office said on Thursday (June 8) it has credible reports that the Islamic State in Iraq and Syria (ISIS) has killed more than 230 civilians trying to flee Iraq's western Mosul since May 26.

Between 50 to 80 more civilians were reportedly killed in a May 31 air strike on the ISIS-controlled Mosul neighbourhood of Zanjilly, said a statement from the office of United Nations human rights chief Zeid Ra'ad Al Hussein.

Mr Zeid had on Tuesday (June 6) accused the militants of killing 163 civilians on June 1 in Mosul's al-Shifa neighbourhood.

Thursday's (June 8) statement detailed two new allegations, including a May 26 incident where ISIS reportedly shot dead 27 people trying to escape al-Shifa, including five children.

On June 3, the group allegedly killed another 41 civilians in the same neighbourhood as they ran towards Iraqi troops, according to the rights office.

"Shooting children as they try to run to safety with their families - there are no words of condemnation strong enough for such despicable acts", Mr Zeid said.

Targeting civilians "who are not directly taking part in hostilities, are war crimes", the statement added.

ISIS seized Mosul in 2014, and the operation that began last October to retake the city has displaced hundreds of thousands of people.

Iraqi forces have retaken all but a handful of areas around the Old City in western Mosul, but the extremists are fighting in densely populated areas, and have used civilians as human shields at various points in the battle.

Several reports in recent weeks, including Pentagon investigations, have found that civilians have repeatedly been killed by air strikes from the anti-ISIS coalition supporting Iraqi troops.

Mr Zeid again urged the coalition "to ensure that their operations comply fully with international humanitarian law and that all possible measures are taken to avoid the loss of civilian lives", reiterating a plea he has made throughout the battle for Mosul.