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Brazil lab which used dogs for drug testing shuts down

Masked demonstrators link arms as they stand by police blocking the entrance to the Instituto Royal laboratory during their protest against drug testing on animals in Sao Roque, Brazil, on Saturday, Oct 19, 2013. -- FILE PHOTO: AP
Masked demonstrators link arms as they stand by police blocking the entrance to the Instituto Royal laboratory during their protest against drug testing on animals in Sao Roque, Brazil, on Saturday, Oct 19, 2013. -- FILE PHOTO: AP
Demonstrators help a fellow protester affected by tear gas fired by police guarding the Instituto Royal laboratory during their protest against drug testing on animals in Sao Roque, Brazil, on Saturday, Oct 19, 2013. -- FILE PHOTO: AP
Demonstrators help a fellow protester affected by tear gas fired by police guarding the Instituto Royal laboratory during their protest against drug testing on animals in Sao Roque, Brazil, on Saturday, Oct 19, 2013. -- FILE PHOTO: AP
Demonstrators run away from the Instituto Royal laboratory to escape tear gas fired by police, as a police car burns along a road leading to the lab in Sao Roque, Brazil, on Saturday, Oct 19, 2013. -- FILE PHOTO: AP
Demonstrators run away from the Instituto Royal laboratory to escape tear gas fired by police, as a police car burns along a road leading to the lab in Sao Roque, Brazil, on Saturday, Oct 19, 2013. -- FILE PHOTO: AP
A police car burns after it was set on fire by demonstrators protesting drug testing on animals at the Instituto Royal laboratory in Sao Roque, Brazil, on Saturday, Oct 19, 2013. -- FILE PHOTO: AP
A police car burns after it was set on fire by demonstrators protesting drug testing on animals at the Instituto Royal laboratory in Sao Roque, Brazil, on Saturday, Oct 19, 2013. -- FILE PHOTO: AP
A demonstrator places a sticker of a dog that reads in Portuguese "Say no to vivisection!" on the shield of a police officer standing guard outside the Instituto Royal laboratory during a protest against drug testing on animals in Sao Roque, Brazil,
A demonstrator places a sticker of a dog that reads in Portuguese "Say no to vivisection!" on the shield of a police officer standing guard outside the Instituto Royal laboratory during a protest against drug testing on animals in Sao Roque, Brazil, on Saturday, Oct 19, 2013. -- FILE PHOTO: AP
Demonstrators protest against the use of animals in drug testing by the Royal Institute in Sao Roque, some 60km of Sao Paulo, Brazil on Oct 19, 2013. The state laboratory which was recently invaded by animal rights activists to free 200 dogs use
Demonstrators protest against the use of animals in drug testing by the Royal Institute in Sao Roque, some 60km of Sao Paulo, Brazil on Oct 19, 2013. The state laboratory which was recently invaded by animal rights activists to free 200 dogs used for drug testing shut down on Wednesday, ending 10 years of research. -- FILE PHOTO: AFP 

SAO PAULO (AFP) - A Sao Paulo state laboratory which was recently invaded by animal rights activists to free 200 dogs used for drug testing shut down on Wednesday, ending 10 years of research.

The Instituto Royal lab said in a statement that the shutdown resulted from "high and irreparable losses and the damage caused by the October 18 invasion which led to the loss of all the animals and 10 years of research."

On that day, activists stormed the lab in Sao Roque, 60km from Sao Paulo, and freed some 200 Beagle dogs used for drug testing.

Most of the animals had their skins shaven and one was found dead, frozen in liquid nitrogen and with signs of mutilation.

Part of the lab installations were vandalised and a subsequent demonstration outside the lab degenerated into clashes between protesters and police.

The institute stressed that the resulting security crisis had "endangered the physical and moral integrity" of its 85 employees who had to be laid off.

Animal testing for scientific research is legal in Brazil and is regulated in line with international norms.