PARIS (Reuters) - Britain's Andy Murray has his best chance of winning the French Open this year, according to American great John McEnroe.

The second seed, who beat world No. 1 Novak Djokovic to claim the Italian Open on clay in Rome last month, faces defending champion Stan Wawrinka in the semi-finals at Roland Garros later on Friday (June 3).

The 29-year-old Scot will be hoping to advance to the final for a first time after tasting semi-final defeat three times previously. And with nine-time French Open champion Rafa Nadal out through injury, Murray's chances have greatly improved.

"Maybe Andy's best chance to win the French ever could be this year," said seven-time Major winner McEnroe, who is working as a commentator in Paris.

"I don't know if he's going to be able to keep this up, so to me he has got his best shot ever.

"He has arguably been coming up against the three greatest guys who ever lived. So he has gotten a lot better and he can take pride in that. He can still add on a couple of Majors."

Murray has won eight of his 15 encounters against Switzerland's Wawrinka.

Serbia's Djokovic, who has never won the French Open, takes on Austrian Dominic Thiem in the other semi-final on Friday.