Wuhan, China (AFP) - World No. 4 Agnieszka Radwanska swept into the third round of the Wuhan Open on Tuesday as former US Open finalist Roberta Vinci became the tournament's first seeded casualty.

One-time Wimbledon runner-up Radwanska defeated Ekaterina Makarova of Russia 6-4, 6-1.

Italy's Vinci, ranked 15th, was ousted by Yaroslava Shvedova 7-5, 6-2 - the second time this year she has lost to the Kazakh.

Radwanska could next meet an in-form Caroline Wozniacki in the third round at the US$2.6 million (S$3.54 million) hard-court event.

Former world No. 1 Wozniacki knocked out the Pole in the semi-finals of the Pan Pacific Open in Tokyo last week in three sets, en route to her first title of the year.

She meets qualifier Katerina Siniakova in the second round later on Tuesday.

American Madison Brengle fell to 10th-ranked Svetlana Kuznetsova of Russia 6-0, 6-4.