HUY, BELGIUM • Fabian Cancellara withdrew from the Tour de France after crashing in the third stage, which was neutralised for about 10 minutes on Monday following a pile-up of some two dozen riders.
FDJ rider William Bonnet of France was put in a neck brace after falling off his bicycle when it apparently touched a wheel.
Others around him were also brought down in a wild flurry of flying bikes and bodies.
Cancellara, who started the day with the leader's yellow jersey, was one of several top names to hit the tarmac, along with Australian Simon Gerrans and Dutchman Tom Dumoulin, who also had to abandon the famous race.
"Just left the hospital with a huge disappointment #TDF2015 is over," Cancellara tweeted. The Swiss' Trek Factory team said he broke two vertebrae in his lower back.
TIME IS OF ESSENCE
This fracture means he needs to undergo surgery quickly to stabilise the vertebrae and avoid neurological consequences.
THIERRY BRICAUD, FDJ sports director on the injury suffered by William Bonnet
When organisers neutralise part of a stage, riders must move at minimal pace and no breakaways or time gains can be attempted.
Bonnet was conscious when he was taken away by medical staff on a stretcher. "He's lucid, he's wearing a neck brace out of precaution," said FDJ sports director Thierry Bricaud. The team said Bonnet suffered a broken cervical vertebra.
"This fracture means he needs to undergo surgery quickly to stabilise the vertebrae and avoid neurological consequences," FDJ said in a statement. "But the fracture in itself is not serious."
At one point, Team Sky riders accelerated before Cancellara made his way back to a bunch that was riding at the minimum pace required when a race is neutralised.
Organisers then decided to stop the race altogether and the peloton came to a halt 55km from the finish before resuming the stage.
"Due to the extraordinary circumstances of the crash at a very high speed, the race was neutralised to allow the injured riders to get back in the peloton," organisers said.
"Twenty-five minutes after the crash, a new start was given at the top of the Cote de Bohisseau with 50km to go."
Sky manager Dave Brailsford said: "It was a good decision. I like to see people who look at the rules and understand the situation and contextualise their decisions based on the current situation that they're in."
TOUR DE FRANCE
Stage 5: StarHub Ch212, 8.15pm