The second victim who died of dengue this year is believed to be a man in his 60s.
The Straits Times understands that he lived in Ang Mo Kio.
He died on Sunday at the Tan Tock Seng Hospital (TTSH).
The Ministry of Health said it would give more details later on Sunday.
On May 29, Ang Yong Han, 20, died of dengue - the first case this year. The only child of a vegetable wholesaler and a fruit seller fell ill on May 22. He died of dengue shock syndrome at TTSH.