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Previously known drug could help treat leukaemia better: NUS study

Published on Aug 25, 2014 12:39 PM

SINGAPORE - Scientists from the National University of Singapore (NUS) have uncovered a possible new way of treating leukaemia that could save more sufferers of the deadly cancer of the blood.

The team from the university's Cancer Science Institute of Singapore (CSI Singapore) suspect that a previously known drug called a PARP inhibitor, normally used to treat only types of cancer that cause damaged DNA, will prove effective in treating leukaemia when used together with standard chemotherapy drugs.

This is because in leukaemia, a gene known as RUNX is often mutated. This same gene, the scientists found, is responsible for repairing damaged DNA.

Leukaemia was not previously thought to be associated with damaged DNA, but the scientists now think it could be.

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