Singapore shares dropped 26.03 points, or 0.8 per cent, by midday on Thursday to 3,222.64, in line with falls across the region.
Asian bourses have snapped their longest winning streak in six weeks, amid mixed corporate earnings and after economists predicted the Federal Reserve will reduce stimulus next month.
Some 1.08 billion shares changed hands in Singapore, valued at $542.5 million.
Losers outnumbered gainers 181 to 141.
Innopac was the most active stock on the Singapore bourse, rising 0.1 cent to 15.2 cents.