Lab mice breakthrough offers Alzheimer's hope
PARIS (AFP) - Scientists on Thursday said they had a drug that in mice helped prevent prion disease and may also work on Alzheimer's, Parkinson's and other brain disorders that share a similar mechanism.
Still at a very early and experimental stage, the drug blocks disruption of the brain's defence system, something that boosts neurodegenerative disease.
Many of these crippling and tragic diseases start with the buildup of rogue, scrunched-up proteins in the brain.
The organ's response to this is to switch on a defence mechanism called the unfolded protein response, or UPR.