Genetic causes of schizophrenia are multiple: Study
PARIS (AFP) - Schizophrenia is caused by a large number of rare genetic mutations rather than a few, easily-identifiable faulty genes, said scientists who compiled the world's largest database on the debilitating disorder.
Two studies published Wednesday in the journal Nature said the genetic triggers for the mental illness that affects about one in 100 people were far more complex than previously thought.
Gathering data from nearly 7,000 people in Bulgaria and Sweden, two teams of scientists said genes implicated in schizophrenia worked in clusters to disrupt specific proteins.
They tend to be part of gene networks that govern signalling between brain cells, or deal with learning and memory, the researchers said.