BANGKOK (AFP) - Thai premier Yingluck Shinawatra appealed on Tuesday for anti-government groups to end ongoing street protests after the parliamentary defeat of an amnesty bill failed to defuse political tensions.

The bill, which critics say was aimed at allowing divisive former premier Thaksin Shinawatra to return home from self-exile, was rejected by senators in a unanimous vote late Monday.

Anger over the amnesty proposal saw around 50,000 people cluster in the political heart of Bangkok late into the night, with some 2,500 anti-government protesters remaining on the streets on Tuesday.

The opposition Democrat Party, which is seen as benefiting from the protests, has called for a three-day nationwide strike starting on Wednesday despite assurances from the ruling Puea Thai party not to revive the bill.

Prime Minister Yingluck - who is Thaksin's sister - urged demonstrators to reject the strike and end their protest.

"As many of their demands have been met, I plead for those protesting to stop," she told reporters, appealing to the public to give her government time to run the country.

Experts say the ill-fated bill has damaged Ms Yingluck's administration and helped the opposition and anti-government groups - who have come out in force for nearly a fortnight.

The visceral reaction to the proposed amnesty has brought a new round of street politics in Thailand, where several bouts of rival protests since Thaksin's government was deposed in an army coup in 2006 have periodically brought chaos to the kingdom.

"The Democrats are now trying to enable conditions on the street to prod a judicial intervention... to upend Yingluck's government," said Mr Thitinan Pongsudhirak, director of the Institute of Security and International Studies at Bangkok's Chulalongkorn University.

Predicting the anti-government protesters will try to hold their ground until early December, Mr Thitinan described the situation "as extreme brinkmanship" aimed at "provoking Ms Yingluck's government into an over-reaction".